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CG12128 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36042, updated on 9-Dec-2024

Summary

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Official Symbol
CG12128provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033473
Locus tag
Dmel_CG12128
See related
AllianceGenome:FB:FBgn0033473
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12128
Summary
Predicted to enable RNA methyltransferase activity. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; gut section; and mesoderm. Orthologous to human SPOUT1 (SPOUT domain containing methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG12128 in Genome Data Viewer
Location:
46D4-46D6; 2-61 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10026839..10030668)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5914344..5918173)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Protein kinase, cAMP-dependent, regulatory subunit type 2 Neighboring gene mir-4967 stem loop Neighboring gene long non-coding RNA:CR44294 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene oysgedart Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster. Szlanka T, et al. G3 (Bethesda), 2024 Sep 4. PMID 38985658, Free PMC Article
  2. Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells. Eliazer S, et al. PLoS Genet, 2014 Mar. PMID 24625679, Free PMC Article
  3. MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila. Daneshvar K, et al. Biol Open, 2013 Jan 15. PMID 23336071, Free PMC Article
  4. Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. Friedman AA, et al. Sci Signal, 2011 Oct 25. PMID 22028469, Free PMC Article
  5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA methyltransferase activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12128-PA
CG12128-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10026839..10030668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206068.2 → NP_995790.1  uncharacterized protein Dmel_CG12128, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995790.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z831, Q8MYV2
    Conserved Domains (1) summary
    cl12077
    Location:6 → 126
    Methyltrn_RNA_3; Putative RNA methyltransferase

  2. NM_136699.4 → NP_610543.1  uncharacterized protein Dmel_CG12128, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610543.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z830, Q8MSZ6
    Related
    FBpp0087481
    Conserved Domains (1) summary
    pfam02598
    Location:74 → 361
    Methyltrn_RNA_3; Putative RNA methyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z830 A1Z830
A1Z831 A1Z831
Q8MSZ6 Q8MSZ6
Q8MYV2 Q8MYV2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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