U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Medag mesenteric estrogen-dependent adipogenesis [ Rattus norvegicus (Norway rat) ]

Gene ID: 360757, updated on 27-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Medagprovided by RGD
Official Full Name
mesenteric estrogen-dependent adipogenesisprovided by RGD
Primary source
RGD:1307396
See related
EnsemblRapid:ENSRNOG00000000906 AllianceGenome:RGD:1307396
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307396
Summary
Predicted to be involved in positive regulation of fat cell differentiation. Predicted to be active in cytoplasm. Orthologous to human MEDAG (mesenteric estrogen dependent adipogenesis). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 94.9), Adrenal (RPKM 94.3) and 7 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Medag in Genome Data Viewer
Location:
12p11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (10649526..10670913, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (5613191..5634583, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (6711745..6730959, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481257 Neighboring gene WD40 repeat domain 95 like Neighboring gene testis expressed 26 Neighboring gene uncharacterized LOC102551556 Neighboring gene ribosomal protein L28, pseudogene 11

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Novel genes of visceral adiposity: identification of mouse and human mesenteric estrogen-dependent adipose (MEDA)-4 gene and its adipogenic function. Zhang H, et al. Endocrinology, 2012 Jun. PMID 22510272
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in positive regulation of fat cell differentiation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
mesenteric estrogen-dependent adipogenesis protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398808.1 → NP_001385737.1  mesenteric estrogen-dependent adipogenesis protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    D3ZTT1
    Related
    ENSRNOP00000103199.1, ENSRNOT00000156087.1

  2. NM_001398809.1 → NP_001385738.1  mesenteric estrogen-dependent adipogenesis protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A6K165
    Related
    ENSRNOP00000001205.6, ENSRNOT00000001205.9

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    10649526..10670913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools