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CG11777 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36108, updated on 9-Dec-2024

Summary

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Official Symbol
CG11777provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033527
Locus tag
Dmel_CG11777
See related
AllianceGenome:FB:FBgn0033527
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE61564; cg11777; Dmel\CG11777
Summary
Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein polyubiquitination. Predicted to be part of catalytic step 2 spliceosome. Is expressed in organism. Orthologous to human PPIL3 (peptidylprolyl isomerase like 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG11777 in Genome Data Viewer
Location:
47A9-47A9; 2-62 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10468616..10469643)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6356121..6357148)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene G protein alpha subunit o Neighboring gene Cytochrome P450 49a1 Neighboring gene Chromatin assembly factor 1, p105 subunit Neighboring gene withered Neighboring gene antisense RNA:CR45134 Neighboring gene translin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CAF-1 promotes Notch signaling through epigenetic control of target gene expression during Drosophila development. Yu Z, et al. Development, 2013 Sep. PMID 23942516, Free PMC Article
  2. Mutations of the withered (whd) gene in Drosophila melanogaster confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene. Strub BR, et al. Genome, 2008 Jun. PMID 18521119
  3. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
  4. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article
  5. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables peptidyl-prolyl cis-trans isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein peptidyl-prolyl isomerization IEA
Inferred from Electronic Annotation
more info
  
involved_in protein polyubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catalytic step 2 spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11777-PA
NP_724939.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10468616..10469643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165776.4 → NP_724939.1  uncharacterized protein Dmel_CG11777 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724939.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NN46, Q8MKJ6
    Related
    FBpp0087366
    Conserved Domains (1) summary
    cd01928
    Location:1 → 154
    Cyclophilin_PPIL3_like; Proteins similar to Human cyclophilin-like peptidylprolyl cis- trans isomerase (PPIL3). Members of this family lack a key residue important for cyclosporin binding: the tryptophan residue corresponding to W121 in human hCyP-18a; most members have a ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MKJ6 Q8MKJ6

Gene LinkOut

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