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Git - G protein-coupled receptor kinase interacting ArfGAP

Enables molecular adaptor activity. Involved in several processes, including mushroom body development; positive regulation of hippo signaling; and protein localization to presynapse. Located in cell leading edge; cytoplasm; and presynaptic active zone. Colocalizes with cytoskeleton of presynaptic active zone. Is expressed in several structures, including adult head; dorsal pharyngeal muscle primordium; larval muscle cell; larval muscle system; and somatic muscle primordium. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Orthologous to several human genes including GIT2 (GIT ArfGAP 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa