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Ntpcr nucleoside-triphosphatase, cancer-related [ Rattus norvegicus (Norway rat) ]

Gene ID: 361443, updated on 4-Jan-2025

Summary

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Official Symbol
Ntpcrprovided by RGD
Official Full Name
nucleoside-triphosphatase, cancer-relatedprovided by RGD
Primary source
RGD:1306192
See related
EnsemblRapid:ENSRNOG00000019922 AllianceGenome:RGD:1306192
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306192
Summary
Predicted to enable ribonucleoside triphosphate phosphatase activity. Predicted to be located in mitochondrion. Orthologous to human NTPCR (nucleoside-triphosphatase, cancer-related). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Testes (RPKM 280.0), Muscle (RPKM 145.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ntpcr in Genome Data Viewer
Location:
19q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (70598816..70612580)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (53701496..53715260)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (58565576..58579276)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098601 Neighboring gene microtubule-associated protein 10 Neighboring gene pecanex 2 Neighboring gene involucrin-like Neighboring gene uncharacterized LOC120098634

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mapping the in vitro interactome of cardiac sodium (Na(+) )-calcium (Ca(2+) ) exchanger 1 (NCX1). Lubelwana Hafver T, et al. Proteomics, 2017 Sep. PMID 28755400
  2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
  3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  4. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  5. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ribonucleoside triphosphate phosphatase activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
cancer-related nucleoside-triphosphatase
Names
nucleoside-triphosphatase C1orf57 homolog
NP_001128045.1
XP_038953830.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134573.1 → NP_001128045.1  cancer-related nucleoside-triphosphatase

    See identical proteins and their annotated locations for NP_001128045.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474054
    UniProtKB/TrEMBL
    A0A8I6A3A7, A6KJ39
    Related
    ENSRNOP00000105264.1, ENSRNOT00000141375.1
    Conserved Domains (2) summary
    smart00382
    Location:5 → 61
    AAA; ATPases associated with a variety of cellular activities
    pfam03266
    Location:6 → 184
    NTPase_1; NTPase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    70598816..70612580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039097902.2 → XP_038953830.1  cancer-related nucleoside-triphosphatase isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:24 → 130
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein Strain
Heading Accession and Version

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