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Ceacam12 CEA cell adhesion molecule 12 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361516, updated on 4-Jan-2025

Summary

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Official Symbol
Ceacam12provided by RGD
Official Full Name
CEA cell adhesion molecule 12provided by RGD
Primary source
RGD:1306754
See related
EnsemblRapid:ENSRNOG00000042158 AllianceGenome:RGD:1306754
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Igfl3
Summary
Predicted to be involved in T cell activation and immune response. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Ceacam12 in Genome Data Viewer
Location:
1q21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (87344541..87351596)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (78216471..78223526)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79474809..79481865)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene carcinoembryonic antigen-related cell adhesion molecule 5-like Neighboring gene CEA cell adhesion molecule 11 Neighboring gene uncharacterized LOC134484888 Neighboring gene uncharacterized LOC134482893

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat. Frängsmyr L, et al. Tumour Biol, 1999 Sep-Oct. PMID 10436421
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 3
Names
CEA-related cell adhesion molecule 12
IGF-like family member 3
IGF-like family member 3-like
carcinoembryonic antigen-related cell adhesion molecule 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108474.1 → NP_001101944.1  carcinoembryonic antigen-related cell adhesion molecule 3

    See identical proteins and their annotated locations for NP_001101944.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/TrEMBL
    A0A8J8YCD1, B0BNJ2, D4A2T3
    Related
    ENSRNOP00000047257.5, ENSRNOT00000044927.6
    Conserved Domains (1) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    87344541..87351596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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