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Snx32 sorting nexin 32 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361708, updated on 4-Jan-2025

Summary

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Official Symbol
Snx32provided by RGD
Official Full Name
sorting nexin 32provided by RGD
Primary source
RGD:1560591
See related
EnsemblRapid:ENSRNOG00000026527 AllianceGenome:RGD:1560591
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Snx6b; RGD1560591
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Predicted to be active in endosome. Orthologous to human SNX32 (sorting nexin 32). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 256.0), Brain (RPKM 226.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Snx32 in Genome Data Viewer
Location:
1q43
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212231716..212248127, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (202801090..202818731, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (220873782..220890804, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene MUS81 structure-specific endonuclease subunit Neighboring gene cofilin 1 Neighboring gene MAGE family member B10 Neighboring gene ribosomal protein L37, pseudogene 2 Neighboring gene ovo like transcriptional repressor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sorting nexin 32; sorting nexin-32
Names
sorting nexin 6B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432327.1 → NP_001419256.1  sorting nexin 32 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I6ARA2, F1LU14

  2. NM_001432328.1 → NP_001419257.1  sorting nexin 32 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I6ARA2

  3. NM_001432329.1 → NP_001419258.1  sorting nexin 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    212231716..212248127 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063279880.1 → XP_063135950.1  sorting nexin-32 isoform X4

  2. XM_006230941.5 → XP_006231003.1  sorting nexin-32 isoform X2

    See identical proteins and their annotated locations for XP_006231003.1

    UniProtKB/TrEMBL
    A0A8I6ARA2
    Conserved Domains (2) summary
    cd06892
    Location:34 → 163
    PX_SNX5_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 5 and 6
    cd07621
    Location:180 → 356
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6

  3. XM_039094864.2 → XP_038950792.1  sorting nexin-32 isoform X7

    Conserved Domains (2) summary
    cd06892
    Location:34 → 171
    PX_SNX5_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 5 and 6
    cl12013
    Location:188 → 270
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  4. XM_039094858.2 → XP_038950786.2  sorting nexin-32 isoform X6

  5. XM_341993.10 → XP_341994.5  sorting nexin-32 isoform X3

    Related
    ENSRNOP00000031258.7, ENSRNOT00000036745.8
    Conserved Domains (2) summary
    cd07621
    Location:188 → 408
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:34 → 171
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  6. XM_006230940.5 → XP_006231002.1  sorting nexin-32 isoform X1

    See identical proteins and their annotated locations for XP_006231002.1

    UniProtKB/TrEMBL
    A0A8I6ARA2
    Conserved Domains (2) summary
    cd06892
    Location:34 → 171
    PX_SNX5_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 5 and 6
    cd07621
    Location:188 → 364
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6

  7. XM_017590289.3 → XP_017445778.1  sorting nexin-32 isoform X5

    Conserved Domains (2) summary
    cd07621
    Location:62 → 238
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  8. XM_039094849.2 → XP_038950777.1  sorting nexin-32 isoform X5

    Conserved Domains (2) summary
    cd07621
    Location:62 → 238
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  9. XM_008760202.4 → XP_008758424.1  sorting nexin-32 isoform X5

    See identical proteins and their annotated locations for XP_008758424.1

    Conserved Domains (2) summary
    cd07621
    Location:62 → 238
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  10. XM_039094845.2 → XP_038950773.1  sorting nexin-32 isoform X5

    Conserved Domains (2) summary
    cd07621
    Location:62 → 238
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  11. XM_039094843.2 → XP_038950771.1  sorting nexin-32 isoform X5

    Conserved Domains (2) summary
    cd07621
    Location:62 → 238
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
Nucleotide Protein Strain
Heading Accession and Version

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