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Gtf3c6 general transcription factor 3C subunit 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361858, updated on 4-Jan-2025

Summary

Official Symbol
Gtf3c6provided by RGD
Official Full Name
general transcription factor 3C subunit 6provided by RGD
Primary source
RGD:1307434
See related
EnsemblRapid:ENSRNOG00000000586 AllianceGenome:RGD:1307434
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307434
Summary
Predicted to enable RNA polymerase III general transcription initiation factor activity. Predicted to contribute to DNA binding activity. Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nuclear body. Predicted to be part of transcription factor TFIIIC complex. Orthologous to human GTF3C6 (general transcription factor IIIC subunit 6). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 41.0), Thymus (RPKM 39.7) and 9 other tissues See more
Orthologs
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Genomic context

See Gtf3c6 in Genome Data Viewer
Location:
20q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (45210906..45222888, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (43656400..43668382, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (45347788..45356868, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108349085 Neighboring gene ribosome production factor 2 homolog Neighboring gene small nucleolar RNA SNORA9 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC120098816

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
contributes_to DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase III general transcription initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transcription by RNA polymerase III ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of transcription factor TFIIIC complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of transcription factor TFIIIC complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
general transcription factor 3C polypeptide 6
Names
general transcription factor IIIC, polypeptide 6, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108537.1NP_001102007.1  general transcription factor 3C polypeptide 6

    See identical proteins and their annotated locations for NP_001102007.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474051
    UniProtKB/TrEMBL
    B0K037, F7ENN0
    Related
    ENSRNOP00000000716.6, ENSRNOT00000000716.8
    Conserved Domains (1) summary
    pfam10419
    Location:5386
    TFIIIC_sub6; TFIIIC subunit

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    45210906..45222888 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)