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atos atossa [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36243, updated on 4-Jan-2025

Summary

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Official Symbol
atosprovided by FlyBase
Official Full Name
atossaprovided by FlyBase
Primary source
FLYBASE:FBgn0033638
Locus tag
Dmel_CG9005
See related
AllianceGenome:FB:FBgn0033638
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH05710; CG9005; Dmel\CG9005; mda
Summary
Involved in positive regulation of gene expression. Is active in nucleus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; apoptotic amnioserosa; embryonic/larval midgut primordium; and somatic trunk mesoderm derivative. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See atos in Genome Data Viewer
Location:
48A3-48B2; 2-64 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11619479..11640941, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7506984..7528446, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43907 Neighboring gene Enigma Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila. Mourikis P, et al. Proc Natl Acad Sci U S A, 2006 Jan 31. PMID 16434470, Free PMC Article
  2. Are entrenched characters developmentally constrained? Creating biramous limbs in an insect. Dworkin IM, et al. Evol Dev, 2001 Nov-Dec. PMID 11806638
  3. A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response. Hilsabeck TAU, et al. Geroscience, 2022 Aug. PMID 35381951, Free PMC Article
  4. Enhancer-promoter communication at the Drosophila engrailed locus. Kwon D, et al. Development, 2009 Sep. PMID 19675130, Free PMC Article
  5. Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes. Chow CY, et al. Proc Natl Acad Sci U S A, 2013 May 28. PMID 23667151, Free PMC Article

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of positive regulation of oxidative phosphorylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to endoplasmic reticulum stress HMP PubMed 
Component Evidence Code Pubs
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
atossa
Names
CG9005-PA
CG9005-PB
CG9005-PC
CG9005-PE
atos-PA
atos-PB
atos-PC
atos-PE
medusa

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    11619479..11640941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001169647.3 → NP_001163118.1  atossa, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163118.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JXG9
    Conserved Domains (2) summary
    pfam13889
    Location:1226 → 1290
    Chromosome_seg; Chromosome segregation during meiosis
    pfam13915
    Location:1074 → 1132
    DUF4210; Domain of unknown function (DUF4210)

  2. NM_001382201.1 → NP_001369081.1  atossa, isoform E [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3Q835
    Conserved Domains (2) summary
    pfam13889
    Location:1226 → 1290
    Chromosome_seg; Chromosome segregation during meiosis
    pfam13915
    Location:1074 → 1131
    DUF4210; Domain of unknown function (DUF4210)

  3. NM_001259338.3 → NP_001246267.1  atossa, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246267.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JXG9
    Conserved Domains (2) summary
    pfam13889
    Location:1226 → 1290
    Chromosome_seg; Chromosome segregation during meiosis
    pfam13915
    Location:1074 → 1132
    DUF4210; Domain of unknown function (DUF4210)

  4. NM_136844.4 → NP_610688.1  atossa, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610688.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JXG9
    Related
    FBpp0087191
    Conserved Domains (2) summary
    pfam13889
    Location:1226 → 1290
    Chromosome_seg; Chromosome segregation during meiosis
    pfam13915
    Location:1074 → 1132
    DUF4210; Domain of unknown function (DUF4210)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A6M3Q835 A0A6M3Q835
Q7JXG9.1 Q7JXG9

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