U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pgap4 post-GPI attachment to proteins GalNAc transferase 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362518, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Pgap4provided by RGD
Official Full Name
post-GPI attachment to proteins GalNAc transferase 4provided by RGD
Primary source
RGD:1307218
See related
EnsemblRapid:ENSRNOG00000006800 AllianceGenome:RGD:1307218
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tmem246; RGD1307218
Summary
Predicted to enable glycosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be active in Golgi membrane. Orthologous to human PGAP4 (post-GPI attachment to proteins GalNAc transferase 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 40.6), Heart (RPKM 38.8) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Pgap4 in Genome Data Viewer
Location:
5q22
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (68727422..68742571, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (63931916..63947004, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (64848657..64867925, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478967 Neighboring gene aldolase, fructose-bisphosphate B Neighboring gene ring finger protein 20 Neighboring gene glutamate ionotropic receptor NMDA type subunit 3A Neighboring gene protein phosphatase 3, regulatory subunit B, beta

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain. Hirata T, et al. Nat Commun, 2018 Jan 26. PMID 29374258, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC109354

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables glycosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in GPI anchor biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in GPI anchor biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
post-GPI attachment to proteins factor 4
Names
transmembrane protein 246
transmembrane protein C9orf125 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014190.1 → NP_001014212.1  post-GPI attachment to proteins factor 4

    See identical proteins and their annotated locations for NP_001014212.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089972
    UniProtKB/Swiss-Prot
    Q5EB73
    UniProtKB/TrEMBL
    A6KJD7
    Conserved Domains (1) summary
    cd22190
    Location:25 → 395
    PGAP4; Post-GPI attachment to proteins factor 4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    68727422..68742571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006238158.5 → XP_006238220.1  post-GPI attachment to proteins factor 4 isoform X1

    See identical proteins and their annotated locations for XP_006238220.1

    UniProtKB/Swiss-Prot
    Q5EB73
    UniProtKB/TrEMBL
    A6KJD7
    Related
    ENSRNOP00000008883.5, ENSRNOT00000008883.9
    Conserved Domains (1) summary
    cd22190
    Location:25 → 395
    PGAP4; Post-GPI attachment to proteins factor 4

  2. XM_006238159.5 → XP_006238221.1  post-GPI attachment to proteins factor 4 isoform X1

    See identical proteins and their annotated locations for XP_006238221.1

    UniProtKB/Swiss-Prot
    Q5EB73
    UniProtKB/TrEMBL
    A6KJD7
    Related
    ENSRNOP00000097268.1, ENSRNOT00000104584.2
    Conserved Domains (1) summary
    cd22190
    Location:25 → 395
    PGAP4; Post-GPI attachment to proteins factor 4

  3. XM_017593473.3 → XP_017448962.1  post-GPI attachment to proteins factor 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5EB73
    UniProtKB/TrEMBL
    A6KJD7
    Conserved Domains (1) summary
    cd22190
    Location:25 → 395
    PGAP4; Post-GPI attachment to proteins factor 4

  4. XM_017593474.3 → XP_017448963.1  post-GPI attachment to proteins factor 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5EB73
    UniProtKB/TrEMBL
    A6KJD7
    Conserved Domains (1) summary
    cd22190
    Location:25 → 395
    PGAP4; Post-GPI attachment to proteins factor 4
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5EB73.1 GenPept UniProtKB/Swiss-Prot:Q5EB73

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools