U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfyve21 zinc finger FYVE-type containing 21 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362789, updated on 27-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Zfyve21provided by RGD
Official Full Name
zinc finger FYVE-type containing 21provided by RGD
Primary source
RGD:1311036
See related
EnsemblRapid:ENSRNOG00000012185 AllianceGenome:RGD:1311036
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable metal ion binding activity. Predicted to be located in endosome and focal adhesion. Orthologous to human ZFYVE21 (zinc finger FYVE-type containing 21). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 193.0), Lung (RPKM 171.9) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zfyve21 in Genome Data Viewer
Location:
6q32
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (136695132..136715601)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (130873979..130894618)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (136380968..136400810)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene kinesin light chain 1 Neighboring gene uncharacterized LOC134479261 Neighboring gene X-ray repair cross complementing 3 Neighboring gene protein phosphatase 1, regulatory subunit 13B Neighboring gene UPF0235 protein C15orf40 homolog Neighboring gene atherin-like Neighboring gene uncharacterized LOC120103629 Neighboring gene uncharacterized LOC134479260

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger FYVE domain-containing protein 21
Names
zinc finger, FYVE domain containing 21

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108725.2 → NP_001102195.1  zinc finger FYVE domain-containing protein 21 isoform 2

    See identical proteins and their annotated locations for NP_001102195.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6AFN3, A6KBT7
    Related
    ENSRNOP00000092004.2, ENSRNOT00000094351.2
    Conserved Domains (2) summary
    cd15727
    Location:38 → 101
    FYVE_ZF21; FYVE domain found in zinc finger FYVE domain-containing protein 21 (ZF21) and similar proteins
    pfam16696
    Location:108 → 223
    ZFYVE21_C; Zinc finger FYVE domain-containing protein 21 C-terminus

  2. NM_001399738.1 → NP_001386667.1  zinc finger FYVE domain-containing protein 21 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/Swiss-Prot
    D3ZVP7

  3. NM_001399739.1 → NP_001386668.1  zinc finger FYVE domain-containing protein 21 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    Conserved Domains (2) summary
    cd15727
    Location:38 → 101
    FYVE_ZF21; FYVE domain found in zinc finger FYVE domain-containing protein 21 (ZF21) and similar proteins
    pfam16696
    Location:108 → 228
    ZFYVE21_C; Zinc finger FYVE domain-containing protein 21 C-terminus

  4. NM_001399740.1 → NP_001386669.1  zinc finger FYVE domain-containing protein 21 isofrm 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

RNA

  1. NR_174344.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    136695132..136715601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594237.3 → XP_017449726.1  zinc finger FYVE domain-containing protein 21 isoform X4

    UniProtKB/TrEMBL
    A0A8I6AAK3

  2. XM_063262148.1 → XP_063118218.1  zinc finger FYVE domain-containing protein 21 isoform X6

  3. XM_063262149.1 → XP_063118219.1  zinc finger FYVE domain-containing protein 21 isoform X7

    Related
    ENSRNOP00000090894.1, ENSRNOT00000097439.2

  4. XM_017594236.2 → XP_017449725.1  zinc finger FYVE domain-containing protein 21 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K9E1
    Related
    ENSRNOP00000074963.2, ENSRNOT00000082914.3
    Conserved Domains (2) summary
    cd15727
    Location:38 → 101
    FYVE_ZF21; FYVE domain found in zinc finger FYVE domain-containing protein 21 (ZF21) and similar proteins
    pfam16696
    Location:108 → 247
    ZFYVE21_C; Zinc finger FYVE domain-containing protein 21 C-terminus

  5. XM_017594235.3 → XP_017449724.1  zinc finger FYVE domain-containing protein 21 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K9E1

  6. XM_006240639.5 → XP_006240701.3  zinc finger FYVE domain-containing protein 21 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K9E1

  7. XM_006240641.5 → XP_006240703.3  zinc finger FYVE domain-containing protein 21 isoform X5

    UniProtKB/TrEMBL
    A0A0G2K9E1
    Conserved Domains (2) summary
    cd15727
    Location:38 → 101
    FYVE_ZF21; FYVE domain found in zinc finger FYVE domain-containing protein 21 (ZF21) and similar proteins
    pfam16696
    Location:108 → 246
    ZFYVE21_C; Zinc finger FYVE domain-containing protein 21 C-terminus
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D3ZVP7.1 GenPept UniProtKB/Swiss-Prot:D3ZVP7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools