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RnrS - Ribonucleoside diphosphate reductase small subunit

Enables cysteine-type endopeptidase activator activity involved in apoptotic process. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be part of ribonucleoside-diphosphate reductase complex. Predicted to be active in cytosol. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; gut section; head epidermis primordium; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 5; mitochondrial DNA depletion syndrome 8a; mitochondrial DNA depletion syndrome 8b; and pancreatic cancer. Orthologous to several human genes including RRM2 (ribonucleotide reductase regulatory subunit M2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa