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Ppp1r16a protein phosphatase 1, regulatory subunit 16A [ Rattus norvegicus (Norway rat) ]

Gene ID: 362944, updated on 4-Jan-2025

Summary

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Official Symbol
Ppp1r16aprovided by RGD
Official Full Name
protein phosphatase 1, regulatory subunit 16Aprovided by RGD
Primary source
RGD:1307962
See related
EnsemblRapid:ENSRNOG00000015450 AllianceGenome:RGD:1307962
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable enzyme inhibitor activity and myosin phosphatase regulator activity. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Orthologous to human PPP1R16A (protein phosphatase 1 regulatory subunit 16A). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Lung (RPKM 91.0), Kidney (RPKM 63.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ppp1r16a in Genome Data Viewer
Location:
7q34
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (110272307..110295452)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108391664..108414812)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117734002..117757249)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene Tmem276-zftraf1 readthrough Neighboring gene Transmembrane protein 276 Neighboring gene kinesin family member C2 Neighboring gene forkhead box H1 Neighboring gene glutamic--pyruvic transaminase Neighboring gene major facilitator superfamily domain containing 3 Neighboring gene RecQ like helicase 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables enzyme inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables myosin phosphatase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 16A
Names
protein phosphatase 1, regulatory (inhibitor) subunit 16A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130566.1 → NP_001124038.1  protein phosphatase 1 regulatory subunit 16A

    See identical proteins and their annotated locations for NP_001124038.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473950
    UniProtKB/TrEMBL
    A0A8I6A2T7, A6HSC4
    Related
    ENSRNOP00000020768.2, ENSRNOT00000020768.5
    Conserved Domains (4) summary
    cd00204
    Location:99 → 286
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:76 → 168
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:205 → 253
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:75 → 102
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    110272307..110295452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263876.1 → XP_063119946.1  protein phosphatase 1 regulatory subunit 16A isoform X1

    UniProtKB/TrEMBL
    A0A8I6A2T7, D3ZVR8
Nucleotide Protein Strain
Heading Accession and Version

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