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Bltp3b bridge-like lipid transfer protein family member 3B [ Rattus norvegicus (Norway rat) ]

Gene ID: 363009, updated on 27-Nov-2024

Summary

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Official Symbol
Bltp3bprovided by RGD
Official Full Name
bridge-like lipid transfer protein family member 3Bprovided by RGD
Primary source
RGD:1594520
See related
EnsemblRapid:ENSRNOG00000050317 AllianceGenome:RGD:1594520
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Uhrf1bp1l
Summary
Predicted to enable GARP complex binding activity; lipid transfer activity; and protein homodimerization activity. Predicted to be involved in early endosome to Golgi transport and intermembrane lipid transfer. Predicted to be located in cytosol and early endosome. Orthologous to human BLTP3B (bridge-like lipid transfer protein family member 3B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 588.9), Kidney (RPKM 156.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Bltp3b in Genome Data Viewer
Location:
7q13
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (26068948..26149033)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (24181635..24261720)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (30408519..30455783)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479655 Neighboring gene actin related protein 6 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC134479858

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A novel syntaxin 6-interacting protein, SHIP164, regulates syntaxin 6-dependent sorting from early endosomes. Otto GP, et al. Traffic, 2010 May. PMID 20163565
  2. JUNB-FBXO21-ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy. Lin Z, et al. Aging Cell, 2021 Feb. PMID 33450132, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GARP complex binding ISO
Inferred from Sequence Orthology
more info
  
enables lipid transfer activity ISO
Inferred from Sequence Orthology
more info
  
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in early endosome to Golgi transport ISO
Inferred from Sequence Orthology
more info
  
involved_in intermembrane lipid transfer ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in early endosome ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
bridge-like lipid transfer protein family member 3B
Names
UHRF1 (ICBP90) binding protein 1-like
UHRF1 binding protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108753.1 → NP_001102223.1  bridge-like lipid transfer protein family member 3B

    See identical proteins and their annotated locations for NP_001102223.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473960
    UniProtKB/TrEMBL
    A0A8I5Y0N1, A6IFS5, M0R8V0
    Conserved Domains (1) summary
    pfam12624
    Location:3 → 89
    Chorein_N; N-terminal region of Chorein or VPS13

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    26068948..26149033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079668.2 → XP_038935596.1  bridge-like lipid transfer protein family member 3B isoform X3

    UniProtKB/TrEMBL
    A0A8I5Y0N1, A0A8I5ZSC2
    Related
    ENSRNOP00000081344.1, ENSRNOT00000118426.2
    Conserved Domains (1) summary
    pfam12624
    Location:5 → 96
    Chorein_N; N-terminal region of Chorein or VPS13

  2. XM_063264009.1 → XP_063120079.1  bridge-like lipid transfer protein family member 3B isoform X1

    Related
    ENSRNOP00000065905.4, ENSRNOT00000072733.4

  3. XM_039079667.2 → XP_038935595.1  bridge-like lipid transfer protein family member 3B isoform X2

    UniProtKB/TrEMBL
    A0A8I5Y0N1, A6IFS6
    Related
    ENSRNOP00000077042.1, ENSRNOT00000096260.2
Nucleotide Protein Strain
Heading Accession and Version

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