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Dyb - Dystrobrevin

Predicted to be a structural constituent of muscle. Involved in maintenance of presynaptic active zone structure and regulation of neurotransmitter secretion. Located in neuromuscular junction. Is expressed in several structures, including adult head; embryonic epidermis; embryonic/larval midgut primordium; ganglia; and larval somatic muscle cell. Human ortholog(s) of this gene implicated in cardiomyopathy and left ventricular noncompaction. Orthologous to several human genes including DTNA (dystrobrevin alpha). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa