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CG8569 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36376, updated on 9-Dec-2024

Summary

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Official Symbol
CG8569provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033752
Locus tag
Dmel_CG8569
See related
AllianceGenome:FB:FBgn0033752
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8569
Summary
Predicted to enable methylated histone binding activity. Predicted to be involved in regulation of signal transduction and regulation of transcription elongation by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 30. Orthologous to human ZMYND11 (zinc finger MYND-type containing 11). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG8569 in Genome Data Viewer
Location:
49A10-49A10; 2-67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12519166..12521624)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8406671..8409129)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene achintya Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene frazzled Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. Nim HT, et al. Genome Biol, 2021 Dec 15. PMID 34906219, Free PMC Article
  2. DEAF-1 function is essential for the early embryonic development of Drosophila. Veraksa A, et al. Genesis, 2002 Jun. PMID 12112874
  3. Functional genomic analysis of the periodic transcriptome in the developing Drosophila wing. Liang L, et al. Dev Cell, 2014 Apr 14. PMID 24684830
  4. The genetic makeup of the Drosophila piRNA pathway. Handler D, et al. Mol Cell, 2013 Jun 6. PMID 23665231, Free PMC Article
  5. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables methylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8569-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12519166..12521624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136951.3 → NP_610795.1  uncharacterized protein Dmel_CG8569 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610795.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K264
    Related
    FBpp0087051
    Conserved Domains (4) summary
    cd05841
    Location:366 → 451
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:243 → 350
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:570 → 604
    zf-MYND; MYND finger
    cl22851
    Location:85 → 120
    PHD_SF; PHD finger superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K264 Q7K264

Gene LinkOut

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