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stil stand still [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36380, updated on 9-Dec-2024

Summary

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Official Symbol
stilprovided by FlyBase
Official Full Name
stand stillprovided by FlyBase
Primary source
FLYBASE:FBgn0003527
Locus tag
Dmel_CG8592
See related
AllianceGenome:FB:FBgn0003527
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
152072_at; CG8592; Dmel\CG8592; Stil; Y10276
Summary
Enables chromatin binding activity. Involved in several processes, including female sex determination; germ-line sex determination; and positive regulation of DNA-templated transcription. Located in chromatin. Is expressed in germarium; germline cell; gonad; and primary spermatocyte cyst. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See stil in Genome Data Viewer
Location:
49B5-49B5; 2-67 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12570367..12571883)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8457872..8459388)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 301a1 Neighboring gene Adenylate kinase 6 Neighboring gene Chloride channel-b Neighboring gene Sin3A Neighboring gene long non-coding RNA:CR30055

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Blocked endocytotic uptake by the oocyte causes accumulation of vitellogenins in the haemolymph of the female-sterile mutants quitPX61 and stand stillPS34 of Drosophila. Gutzeit HO, et al. Cell Tissue Res, 1994 Feb. PMID 8111838
  2. Mutations in the gene stand still disrupt germ cell differentiation in Drosophila ovaries. Mulligan PK, et al. Dev Genet, 1996. PMID 8754283
  3. Comparison of genome architecture at two stages of male germline cell differentiation in Drosophila. Ilyin AA, et al. Nucleic Acids Res, 2022 Apr 8. PMID 35166842, Free PMC Article
  4. PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall. Moyer TC, et al. Elife, 2019 May 22. PMID 31115335, Free PMC Article
  5. The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability. Pennetta G, et al. Dev Genes Evol, 1998 Nov. PMID 9799435

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in female sex determination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in female sex differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in germ-line sex determination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in oogenesis HMP PubMed 
involved_in positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
stand still
Names
CG8592-PA
stil-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12570367..12571883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057404.4 → NP_476752.1  stand still [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476752.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P92189, Q9V6D8
    Related
    FBpp0086938
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P92189.2 P92189

Gene LinkOut

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