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Obp49a Odorant-binding protein 49a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36399, updated on 4-Jan-2025

Summary

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Official Symbol
Obp49aprovided by FlyBase
Official Full Name
Odorant-binding protein 49aprovided by FlyBase
Primary source
FLYBASE:FBgn0050052
Locus tag
Dmel_CG30052
See related
AllianceGenome:FB:FBgn0050052
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH25962; CG30052; CG8769; DmelObp49a; Dmel\CG30052; obp49a; Obp49A; OBP49a
Summary
Predicted to enable odorant binding activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in extracellular region. Is expressed in labellar taste bristle and labellum. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Obp49a in Genome Data Viewer
Location:
49B12-49B12; 2-67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12690059..12690955, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8577564..8578460, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Nucleoporin 188kDa Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Wake-up-call

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conservation of the behavioral and transcriptional response to social experience among Drosophilids. Shultzaberger RK, et al. Genes Brain Behav, 2019 Jan. PMID 29797548, Free PMC Article
  2. Allelic imbalance in Drosophila hybrid heads: exons, isoforms, and evolution. Graze RM, et al. Mol Biol Evol, 2012 Jun. PMID 22319150, Free PMC Article
  3. An odorant-binding protein required for suppression of sweet taste by bitter chemicals. Jeong YT, et al. Neuron, 2013 Aug 21. PMID 23972598, Free PMC Article
  4. Regulatory divergence in Drosophila melanogaster and D. simulans, a genomewide analysis of allele-specific expression. Graze RM, et al. Genetics, 2009 Oct. PMID 19667135, Free PMC Article
  5. "Plus-C" odorant-binding protein genes in two Drosophila species and the malaria mosquito Anopheles gambiae. Zhou JJ, et al. Gene, 2004 Feb 18. PMID 14960367

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study showed that Obp49a required for suppression of sweet taste by bitter chemicals.
    Title: An odorant-binding protein required for suppression of sweet taste by bitter chemicals.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
Odorant-binding protein 49a
Names
CG30052-PA
Obp49a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12690059..12690955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136968.2 → NP_610812.1  Odorant-binding protein 49a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610812.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JVM1
    Related
    FBpp0086985
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JVM1 Q7JVM1

Gene LinkOut

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