Or49b Odorant receptor 49b [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Or49bprovided by FlyBase
Official Full Name: Odorant receptor 49bprovided by FlyBase
Primary source: FLYBASE:FBgn0028963
Locus tag: Dmel_CG17584
See related: AllianceGenome:FB:FBgn0028963
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 49b; 49D.1; AN13; CG17584; Dmel\CG17584; DmOr49b; DOR105; Or-49b; OR49b
Summary: Enables ionotropic olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Located in plasma membrane. Is expressed in adult olfactory receptor neuron Or49b; antennal basiconic sensillum ab6; and antennal lobe glomerulus VA5. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (12842665..12844704)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (8730170..8732209)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Impacts of OrX and cAMP-insensitive Orco to the insect olfactory heteromer activity.
Title: Impacts of OrX and cAMP-insensitive Orco to the insect olfactory heteromer activity.
Identification and functional characterization of olfactory indolergic receptors in Drosophila melanogaster.
Title: Identification and functional characterization of olfactory indolergic receptors in Drosophila melanogaster.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ionotropic olfactory receptor activity	HDA more info	PubMed
enables odorant binding	IEA Inferred from Electronic Annotation more info
enables odorant binding	ISS Inferred from Sequence or Structural Similarity more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell	HDA more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info
involved_in sensory perception of smell	IEA Inferred from Electronic Annotation more info
involved_in sensory perception of smell	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in dendrite membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
located_in plasma membrane	HDA more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info