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Zfp524 zinc finger protein 524 [ Rattus norvegicus (Norway rat) ]

Gene ID: 365179, updated on 9-Dec-2024

Summary

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Official Symbol
Zfp524provided by RGD
Official Full Name
zinc finger protein 524provided by RGD
Primary source
RGD:1565485
See related
EnsemblRapid:ENSRNOG00000016565 AllianceGenome:RGD:1565485
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf524; RGD1565485
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF524 (zinc finger protein 524). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Kidney (RPKM 35.7), Heart (RPKM 34.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp524 in Genome Data Viewer
Location:
1q12
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (77853648..77856886, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (68824803..68828363, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72376381..72379884, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 865 Neighboring gene zinc finger protein 865 Neighboring gene FLT3-interacting zinc finger 1 Neighboring gene zinc finger protein 579

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 524

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108905.1 → NP_001102375.1  zinc finger protein 524

    See identical proteins and their annotated locations for NP_001102375.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474075
    UniProtKB/TrEMBL
    A6KNR2
    Related
    ENSRNOP00000069116.3, ENSRNOT00000022193.8
    Conserved Domains (3) summary
    COG5048
    Location:102 → 218
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:139 → 159
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:123 → 148
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    77853648..77856886 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008758958.4 → XP_008757180.1  zinc finger protein 524 isoform X1

    See identical proteins and their annotated locations for XP_008757180.1

    UniProtKB/TrEMBL
    A6KNR2
    Conserved Domains (3) summary
    COG5048
    Location:102 → 218
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:139 → 159
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:123 → 148
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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