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Fra10ac1 FRA10A associated CGG repeat 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 365458, updated on 4-Jan-2025

Summary

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Official Symbol
Fra10ac1provided by RGD
Official Full Name
FRA10A associated CGG repeat 1provided by RGD
Primary source
RGD:1309482
See related
EnsemblRapid:ENSRNOG00000015235 AllianceGenome:RGD:1309482
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309482
Summary
Predicted to enable phosphatase activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Orthologous to human FRA10AC1 (FRA10A associated CGG repeat 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 36.6), Kidney (RPKM 30.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fra10ac1 in Genome Data Viewer
Location:
1q53
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (245381538..245413879, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (235969071..236001074, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (256881688..256913617, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene retinol binding protein 4 Neighboring gene phosphodiesterase 6C Neighboring gene RGD1561251 Neighboring gene uncharacterized LOC134483993

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC109644

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
  
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
protein FRA10AC1 homolog
Names
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014246.1 → NP_001014268.1  protein FRA10AC1 homolog

    See identical proteins and their annotated locations for NP_001014268.1

    Status: PROVISIONAL

    Source sequence(s)
    BC090036
    UniProtKB/Swiss-Prot
    Q5FVF1
    Related
    ENSRNOP00000020620.7, ENSRNOT00000020620.8
    Conserved Domains (1) summary
    pfam09725
    Location:104 → 216
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    245381538..245413879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269970.1 → XP_063126040.1  protein FRA10AC1 homolog isoform X7

    UniProtKB/TrEMBL
    A0A8I6GIK3, A6I184
    Related
    ENSRNOP00000090840.1, ENSRNOT00000110182.2

  2. XM_039085664.2 → XP_038941592.1  protein FRA10AC1 homolog isoform X6

    UniProtKB/TrEMBL
    A0A8I5ZMA6
    Conserved Domains (1) summary
    pfam09725
    Location:104 → 216
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  3. XM_008760372.4 → XP_008758594.1  protein FRA10AC1 homolog isoform X4

    UniProtKB/TrEMBL
    A6I184
    Conserved Domains (1) summary
    pfam09725
    Location:111 → 216
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  4. XM_039085649.2 → XP_038941577.1  protein FRA10AC1 homolog isoform X3

    UniProtKB/TrEMBL
    A6I184
    Conserved Domains (1) summary
    pfam09725
    Location:111 → 216
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  5. XM_008760371.4 → XP_008758593.1  protein FRA10AC1 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8L2QAE0
    Related
    ENSRNOP00000079231.2, ENSRNOT00000095503.2
    Conserved Domains (1) summary
    pfam09725
    Location:111 → 223
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  6. XM_039085637.2 → XP_038941565.1  protein FRA10AC1 homolog isoform X1

    Conserved Domains (1) summary
    pfam09725
    Location:111 → 223
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  7. XM_039085661.2 → XP_038941589.1  protein FRA10AC1 homolog isoform X5

    Related
    ENSRNOP00000099843.1, ENSRNOT00000121443.1
    Conserved Domains (1) summary
    pfam09725
    Location:107 → 219
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  8. XM_039085669.2 → XP_038941597.1  protein FRA10AC1 homolog isoform X9

    UniProtKB/TrEMBL
    A6I184
    Conserved Domains (1) summary
    pfam09725
    Location:111 → 216
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  9. XM_039085666.2 → XP_038941594.1  protein FRA10AC1 homolog isoform X8

    Conserved Domains (1) summary
    pfam09725
    Location:111 → 223
    Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

  10. XM_063269976.1 → XP_063126046.1  protein FRA10AC1 homolog isoform X10

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5FVF1.1 GenPept UniProtKB/Swiss-Prot:Q5FVF1

Gene LinkOut

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