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VGAT - Vesicular GABA Transporter

Predicted to enable gamma-aminobutyric acid:proton symporter activity and glycine transmembrane transporter activity. Involved in several processes, including GABAergic synaptic transmission; gamma-aminobutyric acid transport; and visual behavior. Located in synaptic vesicle membrane. Is expressed in several structures, including adult brain; ganglia; optic lobe intrinsic columnar neurons; synaptic neuropil domain; and unpaired neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy and generalized epilepsy with febrile seizures plus. Orthologous to human SLC32A1 (solute carrier family 32 member 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa