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Opa1 - Optic atrophy 1

Predicted to enable GTPase activity and microtubule binding activity. Involved in compound eye morphogenesis; mitochondrial fusion; and positive regulation of mitochondrial fusion. Located in mitochondrion. Is expressed in adult head; adult heart; indirect flight muscle cell; and organism. Used to study optic atrophy. Human ortholog(s) of this gene implicated in Behr syndrome; dominant optic atrophy plus syndrome; mitochondrial DNA depletion syndrome 14; optic atrophy; and optic atrophy 1. Orthologous to human OPA1 (OPA1 mitochondrial dynamin like GTPase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa