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Apmap adipocyte plasma membrane associated protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 366227, updated on 4-Jan-2025

Summary

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Official Symbol
Apmapprovided by RGD
Official Full Name
adipocyte plasma membrane associated proteinprovided by RGD
Primary source
RGD:1308874
See related
EnsemblRapid:ENSRNOG00000006795 AllianceGenome:RGD:1308874
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ab2-305; RGD1308874
Summary
Predicted to enable arylesterase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cell surface and membrane. Orthologous to human APMAP (adipocyte plasma membrane associated protein). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 934.2), Liver (RPKM 460.3) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Apmap in Genome Data Viewer
Location:
3q41
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (159869451..159897727, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (139409021..139437296, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (146376828..146407259, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene galactokinase 1 like 1 Neighboring gene ribosomal protein SA, pseudogene 6 Neighboring gene cystatin F Neighboring gene acyl-CoA synthetase short-chain family member 1 Neighboring gene uncharacterized LOC102547396 Neighboring gene visual system homeobox 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Localization and characterization of the novel protein encoded by C20orf3. Ilhan A, et al. Biochem J, 2008 Sep 15. PMID 18513186
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC125177

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables arylesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables arylesterase activity ISO
Inferred from Sequence Orthology
more info
  
enables strictosidine synthase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell surface ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
adipocyte plasma membrane-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034003.2 → NP_001029175.1  adipocyte plasma membrane-associated protein isoform 3

    See identical proteins and their annotated locations for NP_001029175.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q3KR93, Q7TP48
    UniProtKB/TrEMBL
    A0A8L2Q3J0
    Conserved Domains (4) summary
    COG3386
    Location:33 → 280
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cd05819
    Location:62 → 97
    NHL; NHL repeat [structural motif]
    cl18310
    Location:56 → 244
    NHL; NHL repeat unit of beta-propeller proteins
    cl22863
    Location:161 → 248
    Str_synth; Strictosidine synthase

  2. NM_001398965.1 → NP_001385894.1  adipocyte plasma membrane-associated protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A0A8L2Q3J0, A6KHF4
    Related
    ENSRNOP00000008932.8, ENSRNOT00000008931.10
    Conserved Domains (2) summary
    COG3386
    Location:72 → 319
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cl22863
    Location:200 → 287
    Str_synth; Strictosidine synthase

  3. NM_001398966.1 → NP_001385895.1  adipocyte plasma membrane-associated protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    Related
    ENSRNOP00000111325.1, ENSRNOT00000138959.1
    Conserved Domains (2) summary
    COG3386
    Location:72 → 284
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cl22863
    Location:200 → 280
    Str_synth; Strictosidine synthase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    159869451..159897727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063284289.1 → XP_063140359.1  adipocyte plasma membrane-associated protein isoform X2

    UniProtKB/TrEMBL
    A0A0G2K6G2, A0A8L2Q3J0
    Related
    ENSRNOP00000073800.2, ENSRNOT00000091310.3

  2. XM_063284288.1 → XP_063140358.1  adipocyte plasma membrane-associated protein isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZUF8, A0A8L2Q3J0
    Related
    ENSRNOP00000082165.1, ENSRNOT00000099680.2

  3. XM_063284290.1 → XP_063140360.1  adipocyte plasma membrane-associated protein isoform X3

    UniProtKB/Swiss-Prot
    Q3KR93, Q7TP48
    UniProtKB/TrEMBL
    A0A8L2Q3J0

  4. XM_006235217.4 → XP_006235279.1  adipocyte plasma membrane-associated protein isoform X4

    UniProtKB/TrEMBL
    A0A8L2Q3J0
    Conserved Domains (2) summary
    COG3386
    Location:1 → 243
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cl22863
    Location:124 → 211
    Str_synth; Strictosidine synthase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7TP48.2 GenPept UniProtKB/Swiss-Prot:Q7TP48

Gene LinkOut

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