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jef jet fuel [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36634, updated on 9-Dec-2024

Summary

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Official Symbol
jefprovided by FlyBase
Official Full Name
jet fuelprovided by FlyBase
Primary source
FLYBASE:FBgn0033958
Locus tag
Dmel_CG12858
See related
AllianceGenome:FB:FBgn0033958
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12858; Dmel\CG12858
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in adult head; embryonic head sensory system; ganglia; larval nervous system; and sensory nervous system primordium. Orthologous to human MFSD6 (major facilitator superfamily domain containing 6). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See jef in Genome Data Viewer
Location:
51C1-51C1; 2-72 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14739359..14745335, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10626864..10632840, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene M-spondin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Attacin-A Neighboring gene Drosocin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster. Ceder MM, et al. Front Cell Dev Biol, 2020. PMID 32733888, Free PMC Article
  2. Identification of downstream targets of the bone morphogenetic protein pathway in the Drosophila nervous system. Kim NC, et al. Dev Dyn, 2010 Sep. PMID 20652954
  3. The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods. Denecke SM, et al. Genome Biol Evol, 2020 Aug 1. PMID 32681801, Free PMC Article
  4. Genomic organization of gypsy chromatin insulators in Drosophila melanogaster. Ramos E, et al. Genetics, 2006 Apr. PMID 16452134, Free PMC Article
  5. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Okamoto N, et al. Dev Cell, 2018 Nov 5. PMID 30293839, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
jet fuel
Names
CG12858-PA
CG12858-PB
jef-PA
jef-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    14739359..14745335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259394.2 → NP_001246323.1  jet fuel, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246323.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z9U2, Q8SX39
    Conserved Domains (3) summary
    cd06174
    Location:508 → 681
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:511 → 701
    MFS_1; Major Facilitator Superfamily
    cl21472
    Location:125 → 187
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

  2. NM_137139.2 → NP_610983.1  jet fuel, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610983.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z9U2, Q8SX39
    Related
    FBpp0086605
    Conserved Domains (3) summary
    cd06174
    Location:508 → 681
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:511 → 701
    MFS_1; Major Facilitator Superfamily
    cl21472
    Location:125 → 187
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z9U2 A1Z9U2
Q8SX39 Q8SX39

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