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Cyp6a8 - Cytochrome P450 6a8

Enables alkane 1-monooxygenase activity; fatty acid binding activity; and medium-chain fatty acid omega-1 hydroxylase activity. Involved in insecticide metabolic process; lauric acid metabolic process; and response to caffeine. Located in endomembrane system. Is expressed in adult head; amnioserosa; embryonic/larval Malpighian tubule; and yolk nucleus. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome; cerebral infarction; essential hypertension; familial Mediterranean fever; and leukemia (multiple). Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Cyp6a8

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Species Gene Architecture aa