Ldoc1 LDOC1, regulator of NFKB signaling [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Ldoc1provided by RGD
Full Name: LDOC1, regulator of NFKB signalingprovided by RGD
Primary source: RGD:1565644
See related: EnsemblRapid:ENSRNOG00000003409 AllianceGenome:RGD:1565644
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565644
Summary: Predicted to be involved in cellular response to lipopolysaccharide and cellular response to muramyl dipeptide. Predicted to act upstream of or within maternal placenta development; maternal process involved in parturition; and regulation of growth hormone activity. Predicted to be located in nucleolus and nucleoplasm. Orthologous to human LDOC1 (LDOC1 regulator of NFKB signaling). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 7.9), Brain (RPKM 3.6) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq36

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (144837879..145110607)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (139965509..140074355)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (144699737..144778947)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cellular response to lipopolysaccharide	ISO Inferred from Sequence Orthology more info
involved_in cellular response to muramyl dipeptide	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within maternal placenta development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within maternal process involved in parturition	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of growth hormone activity	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein LDOC1

Names: leucine zipper, down-regulated in cancer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.