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osgepl1 O-sialoglycoprotein endopeptidase-like 1 [ Danio rerio (zebrafish) ]

Gene ID: 368635, updated on 4-Jan-2025

Summary

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Official Symbol
osgepl1provided by ZNC
Official Full Name
O-sialoglycoprotein endopeptidase-like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030616-532
See related
Ensembl:ENSDARG00000000651 AllianceGenome:ZFIN:ZDB-GENE-030616-532
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dz72b14.6
Summary
Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to act upstream of or within tRNA processing. Predicted to be active in mitochondrion. Orthologous to human OSGEPL1 (O-sialoglycoprotein endopeptidase like 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See osgepl1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (41040302..41045873)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (41238515..41244086)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene si:ch211-3o3.7 Neighboring gene myostatin b Neighboring gene PMS1 homolog 1, mismatch repair system component Neighboring gene ORMDL sphingolipid biosynthesis regulator 1 Neighboring gene adenosine deaminase tRNA specific 3 Neighboring gene ankyrin and armadillo repeat containing Neighboring gene U5 spliceosomal RNA Neighboring gene zgc:136439 Neighboring gene asparagine synthetase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC123084

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables N(6)-L-threonylcarbamoyladenine synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables N(6)-L-threonylcarbamoyladenine synthase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA threonylcarbamoyladenosine modification IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA threonylcarbamoyladenosine modification ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial
Names
N6-L-threonylcarbamoyladenine synthase
glycoprotease
probable O-sialoglycoprotein endopeptidase 2
probable tRNA threonylcarbamoyladenosine biosynthesis protein osgepl1
t(6)A synthase
NP_001005301.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005301.1 → NP_001005301.1  tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

    See identical proteins and their annotated locations for NP_001005301.1

    Status: PROVISIONAL

    Source sequence(s)
    AL672217
    UniProtKB/Swiss-Prot
    Q32LQ3, Q8JFR7, Q8JFW3
    Related
    ENSDARP00000001156.8, ENSDART00000000693.9
    Conserved Domains (2) summary
    PRK09604
    Location:26 → 363
    PRK09604; UGMP family protein; Validated
    cl22532
    Location:27 → 157
    Carbam_trans_N; Carbamoyltransferase N-terminus

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    41040302..41045873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q32LQ3.2 GenPept UniProtKB/Swiss-Prot:Q32LQ3

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