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SmydA-6 SET and MYND domain containing, arthropod-specific, member 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36917, updated on 9-Dec-2024

Summary

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Official Symbol
SmydA-6provided by FlyBase
Official Full Name
SET and MYND domain containing, arthropod-specific, member 6provided by FlyBase
Primary source
FLYBASE:FBgn0034183
Locus tag
Dmel_CG9642
See related
AllianceGenome:FB:FBgn0034183
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9642; Dmel\CG9642
Summary
Predicted to enable histone deacetylase binding activity. Predicted to be involved in negative regulation of gene expression. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See SmydA-6 in Genome Data Viewer
Location:
53F1-53F2; 2-81 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17046839..17048794)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12934344..12936299)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 2 Neighboring gene antisense RNA:CR45145 Neighboring gene SET and MYND domain containing, arthropod-specific, member 7 Neighboring gene uncharacterized protein Neighboring gene fat-spondin Neighboring gene teflon

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species. Calpena E, et al. PLoS One, 2015. PMID 26230726, Free PMC Article
  2. A Drosophila Smyd4 homologue is a muscle-specific transcriptional modulator involved in development. Thompson EC, et al. PLoS One, 2008 Aug 20. PMID 18714374, Free PMC Article
  3. Comparative genomic analysis of SET domain family reveals the origin, expansion, and putative function of the arthropod-specific SmydA genes as histone modifiers in insects. Jiang F, et al. Gigascience, 2017 Jun 1. PMID 28444351, Free PMC Article
  4. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Schotta G, et al. Genes Dev, 2004 Jun 1. PMID 15145825, Free PMC Article
  5. Genome features of "Dark-fly", a Drosophila line reared long-term in a dark environment. Izutsu M, et al. PLoS One, 2012. PMID 22432011, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables histone deacetylase binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein-lysine N-methyltransferase activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
SET and MYND domain containing, arthropod-specific, member 6
Names
CG9642-PA
SmydA-6-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17046839..17048794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137338.2 → NP_611182.1  SET and MYND domain containing, arthropod-specific, member 6 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611182.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAP0
    Related
    FBpp0086127
    Conserved Domains (1) summary
    pfam00856
    Location:179 → 244
    SET; SET domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZAP0 A1ZAP0

Gene LinkOut

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