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Vajk4 Vajk4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36950, updated on 9-Dec-2024

Summary

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Official Symbol
Vajk4provided by FlyBase
Official Full Name
Vajk4provided by FlyBase
Primary source
FLYBASE:FBgn0050101
Locus tag
Dmel_CG30101
See related
AllianceGenome:FB:FBgn0050101
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15901; CG30101; CG6564; Dmel\CG30101; FBgn0050101; vajk-4
Summary
Enables chitin binding activity. Predicted to be involved in chitin-based cuticle development. Located in chitin-based extracellular matrix. Is expressed in several structures, including adult head; border follicle cell; embryonic epipharynx; embryonic head epidermis; and epidermis. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Vajk4 in Genome Data Viewer
Location:
54B7-54B7; 2-82 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17408258..17410204, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13295763..13297709, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cathelicidin-like antimicrobial protein Neighboring gene Proteasome alpha5 subunit Neighboring gene connector enhancer of ksr

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila. Cinege G, et al. Insect Biochem Mol Biol, 2017 Aug. PMID 28633893
  2. SoxNeuro and Shavenbaby act cooperatively to shape denticles in the embryonic epidermis of Drosophila. Rizzo NP, et al. Development, 2017 Jun 15. PMID 28506986, Free PMC Article
  3. A conserved gene cluster as a putative functional unit in insect innate immunity. Somogyi K, et al. FEBS Lett, 2010 Nov 5. PMID 20951134
  4. In silico identification of new secretory peptide genes in Drosophila melanogaster. Liu F, et al. Mol Cell Proteomics, 2006 Mar. PMID 16291998
  5. Spaceflight-related suboptimal conditions can accentuate the altered gravity response of Drosophila transcriptome. Herranz R, et al. Mol Ecol, 2010 Oct. PMID 20819157

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables chitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chitin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of chitin-based cuticle ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chitin-based extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chitin-based extracellular matrix IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Vajk4
Names
CG30101-PA
Vajk4-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17408258..17410204 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137361.4 → NP_611205.1  Vajk4 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611205.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K0W4
    Related
    FBpp0086118
    Conserved Domains (1) summary
    PRK10811
    Location:137 → 313
    rne; ribonuclease E; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K0W4 Q7K0W4

Gene LinkOut

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