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Snx16 Sorting nexin 16 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37015, updated on 9-Dec-2024

Summary

Official Symbol
Snx16provided by FlyBase
Official Full Name
Sorting nexin 16provided by FlyBase
Primary source
FLYBASE:FBgn0034265
Locus tag
Dmel_CG6410
See related
AllianceGenome:FB:FBgn0034265
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6410; Dmel\CG6410; DmSNX16; dSnx16; snx16; SNX16
Summary
Predicted to enable phosphatidylinositol binding activity. Involved in positive regulation of synaptic assembly at neuromuscular junction and receptor recycling. Located in early endosome; multivesicular body; and neuromuscular junction. Is active in presynaptic endosome. Is expressed in adult head and organism. Used to study polycythemia due to hypoxia. Orthologous to human SNX16 (sorting nexin 16). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Snx16 in Genome Data Viewer
Location:
54E2-54E2; 2-84 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17725030..17726847, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13612535..13614352, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene U snoRNA host gene 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dachs ligand with SH3s Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene hyccin

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol binding ISM
Inferred from Sequence Model
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in early endosome to late endosome transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endosome to lysosome transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of synaptic assembly at neuromuscular junction IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in receptor recycling IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in receptor recycling IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in multivesicular body IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in presynaptic endosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
sorting nexin 16
Names
CG6410-PA
Snx16-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17725030..17726847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137408.4NP_611252.1  sorting nexin 16 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611252.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JR96
    Related
    FBpp0086045
    Conserved Domains (1) summary
    cd07276
    Location:219329
    PX_SNX16; The phosphoinositide binding Phox Homology domain of Sorting Nexin 16