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C22L TNF-alpha-receptor-like protein [ Vaccinia virus ]

Gene ID: 3707619, updated on 3-Dec-2024

Summary

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Gene symbol
C22L
Gene description
TNF-alpha-receptor-like protein
Locus tag
VACWR004
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Vaccinia virus (strain: WR (Western Reserve))
Lineage
Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Orthopoxvirus
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Genomic context

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Sequence:
NC_006998.1 (5092..5460, complement)

NC_006998.1Genomic Context describing neighboring genes Neighboring gene temporal expression: early/late Neighboring gene TNF-alpha-receptor-like protein Neighboring gene hypothetical protein Neighboring gene ankyrin-like protein Neighboring gene ankyrin-like protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_006998.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumour necrosis factor receptors. Alcam A, et al. J Gen Virol, 1999 Apr. PMID 10211965

GeneRIFs: Gene References Into Functions

General gene information

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Homology

  • ITR paralog: VACWR215, B28R

General protein information

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Preferred Names
TNF-alpha-receptor-like protein
YP_232886.1
  • TNF-alpha-receptor-like protein; host defense modulator, binds host TNF-alpha and exhibits antiapoptotic effects; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006998.1 Reference assembly

    Range
    5092..5460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_232886.1 TNF-alpha-receptor-like [Vaccinia virus]

    See identical proteins and their annotated locations for YP_232886.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P21106, Q76ZJ3
    UniProtKB/TrEMBL
    A0A2I2MDV8, B9U156, O57077, O57290, Q49P85, Q49Q17, Q76PR9, Q76RX0
    Conserved Domains (1) summary
    PHA02637
    Location:1 → 122
    PHA02637; TNF-alpha-receptor-like protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
AAO89283.1

Gene LinkOut

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