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CG33958 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37088, updated on 4-Jan-2025

Summary

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Official Symbol
CG33958provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0053958
Locus tag
Dmel_CG33958
See related
AllianceGenome:FB:FBgn0053958
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14501; CG5719; Dmel\CG33958; GYC
Summary
Predicted to enable guanylate cyclase activity and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG33958 in Genome Data Viewer
Location:
55B12-55B12; 2-84 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18184382..18192851, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14071887..14080356, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene mir-11182 stem loop Neighboring gene no poles Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45147 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The evolution of guanylyl cyclases as multidomain proteins: conserved features of kinase-cyclase domain fusions. Biswas KH, et al. J Mol Evol, 2009 Jun. PMID 19495554
  2. E and M circadian pacemaker neurons use different PDF receptor signalosome components in drosophila. Duvall LB, et al. J Biol Rhythms, 2013 Aug. PMID 23929551, Free PMC Article
  3. Chromatin immunoprecipitation reveals a novel role for the Drosophila SoxNeuro transcription factor in axonal patterning. Girard F, et al. Dev Biol, 2006 Nov 15. PMID 16979619
  4. The Insect Prothoracic Gland as a Model for Steroid Hormone Biosynthesis and Regulation. Ou Q, et al. Cell Rep, 2016 Jun 28. PMID 27320926, Free PMC Article
  5. Function-informed transcriptome analysis of Drosophila renal tubule. Wang J, et al. Genome Biol, 2004. PMID 15345053, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables guanylate cyclase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables guanylate cyclase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cGMP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cGMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in receptor guanylyl cyclase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG33958-PA
NP_001033958.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    18184382..18192851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038869.3 → NP_001033958.1  uncharacterized protein Dmel_CG33958 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033958.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZB47, Q1EC29
    Conserved Domains (4) summary
    smart00044
    Location:459 → 647
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    pfam00211
    Location:485 → 669
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam07701
    Location:439 → 479
    HNOBA; Heme NO binding associated
    pfam08376
    Location:159 → 396
    NIT; Nitrate and nitrite sensing
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZB47 A1ZB47

Gene LinkOut

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