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Pepck2 - Phosphoenolpyruvate carboxykinase 2

Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Involved in glycerol biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in cytosol. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; gut section; and somatic trunk mesoderm derivative. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to several human genes including PCK1 (phosphoenolpyruvate carboxykinase 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa