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5-HT1A - 5-hydroxytryptamine (serotonin) receptor 1A

Enables G protein-coupled serotonin receptor activity. Involved in several processes, including G protein-coupled serotonin receptor signaling pathway; anesthesia-resistant memory; and inter-male aggressive behavior. Predicted to be located in membrane. Predicted to be active in dendrite and plasma membrane. Is expressed in several structures, including adult brain; adult head; larval midline neurons; neurosecretory cell of brain; and serotonergic neurons. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; antisocial personality disorder; anxiety disorder (multiple); depressive disorder (multiple); and substance abuse (multiple). Orthologous to several human genes including HTR1A (5-hydroxytryptamine receptor 1A). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to 5-HT1A

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Species Gene Architecture aa