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CkIIbeta2 Casein kinase II beta2 subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37300, updated on 9-Dec-2024

Summary

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Official Symbol
CkIIbeta2provided by FlyBase
Official Full Name
Casein kinase II beta2 subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0026136
Locus tag
Dmel_CG8914
See related
AllianceGenome:FB:FBgn0026136
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8914; CK2; CK2beta'; CKIIb2; CKIIbeta'; CKIIbeta2; dCK2beta'; Dm-CK2-beta'; DmCK2beta'; DmCKIIbeta'; Dmel\CG8914
Summary
Predicted to enable protein kinase regulator activity. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CkIIbeta2 in Genome Data Viewer
Location:
56F16-56F16; 2-90 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20289545..20290550)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16177050..16178055)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 56F Neighboring gene long non-coding RNA:CR44638 Neighboring gene long non-coding RNA:CR44639

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A gene located at 56F1-2 in Drosophila melanogaster encodes a novel metazoan beta-like subunit of casein kinase II. Bidwai AP, et al. Mol Cell Biol Res Commun, 1999 Apr. PMID 10329473
  2. A gene located at 72A in Drosophila melanogaster encodes a novel zinc-finger protein that interacts with protein kinase CK2. Kalive M, et al. Mol Cell Biochem, 2001 Nov. PMID 11827180
  3. Drosophila protein kinase CK2 is rendered temperature-sensitive by mutations of highly conserved residues flanking the activation segment. Kuntamalla PP, et al. Mol Cell Biochem, 2009 Mar. PMID 19039653, Free PMC Article
  4. CK2(beta)tes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster. Kalmykova AI, et al. Eur J Biochem, 2002 Mar. PMID 11874456
  5. The Drosophila SSL gene is expressed in larvae, pupae, and adults, exhibits sexual dimorphism, and mimics properties of the beta subunit of casein kinase II. Karandikar U, et al. Biochem Biophys Res Commun, 2003 Feb 21. PMID 12589803

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase regulator activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein kinase CK2 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein kinase CK2 complex IEA
Inferred from Electronic Annotation
more info
  
part_of protein kinase CK2 complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
casein kinase II beta2 subunit
Names
CG8914-PA
CkIIbeta2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20289545..20290550
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058059.4 → NP_477407.1  casein kinase II beta2 subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477407.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O96863, Q53XE8, Q9V919
    Related
    FBpp0085590
    Conserved Domains (1) summary
    pfam01214
    Location:9 → 189
    CK_II_beta; Casein kinase II regulatory subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O96863.1 O96863

Gene LinkOut

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