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sktl - skittles

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Involved in several processes, including basement membrane organization; endosome organization; and germ cell development. Located in cell cortex; male germline ring canal; and plasma membrane. Colocalizes with apical plasma membrane. Is expressed in several structures, including anlage in statu nascendi; epithelial furrow; germline cell; gut section; and head epidermis primordium. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to several human genes including PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to sktl

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Species Gene Architecture aa