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krt12.6.S keratin 12, gene 6 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 373761, updated on 4-Jan-2025

Summary

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Official Symbol
krt12.6.S
Official Full Name
keratin 12, gene 6 S homeolog
Primary source
Xenbase:XB-GENE-6252695
Locus tag
XELAEV_18045890mg
See related
EnsemblRapid:ENSXLAG00005025830 AllianceGenome:Xenbase:XB-GENE-6252695
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
xak-c; ak-c-A; xak-c.S
Summary
Predicted to enable structural molecule activity. Acts upstream of or within limb bud formation. Predicted to be located in intermediate filament. Is expressed in dermal system. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See krt12.6.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (1185669..1190695)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (1097115..1102161)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene Keratin 12, gene 4 S homeolog Neighboring gene keratin 12, gene 5 S homeolog Neighboring gene keratin 53 S homeolog Neighboring gene keratin 50 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Metamorphosis-dependent transcriptional regulation of xak-c, a novel Xenopus type I keratin gene. Watanabe Y, et al. Dev Dyn, 2002 Dec. PMID 12454932
  2. Reactivation of larval keratin gene (krt62.L) in blastema epithelium during Xenopus froglet limb regeneration. Satoh A, et al. Dev Biol, 2017 Dec 15. PMID 29079423
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within limb bud formation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
keratin 12, gene 6 S homeolog
Names
adult keratin XAK-C S homeolog
adult-specific keratin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085706.1 → NP_001079175.1  keratin 12, gene 6 S homeolog

    See identical proteins and their annotated locations for NP_001079175.1

    Status: PROVISIONAL

    Source sequence(s)
    AB086829
    UniProtKB/TrEMBL
    A0A974BSB6, Q8AV12
    Related
    ENSXLAP00005076775.1, ENSXLAT00005078366.1
    Conserved Domains (2) summary
    pfam00038
    Location:152 → 464
    Filament; Intermediate filament protein
    pfam09455
    Location:288 → 461
    Cas_DxTHG; CRISPR-associated (Cas) DxTHG family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    1185669..1190695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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