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Sou Souji [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37382, updated on 9-Dec-2024

Summary

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Official Symbol
Souprovided by FlyBase
Official Full Name
Soujiprovided by FlyBase
Primary source
FLYBASE:FBgn0034573
Locus tag
Dmel_CG3295
See related
AllianceGenome:FB:FBgn0034573
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3295; Dmel\CG3295
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Part of GID complex. Is expressed in organism. Orthologous to human RMND5A (required for meiotic nuclear division 5 homolog A) and RMND5B (required for meiotic nuclear division 5 homolog B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Sou in Genome Data Viewer
Location:
57B9-57B9; 2-92 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21015594..21017446, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16903099..16904951, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene grauzone Neighboring gene uncharacterized protein Neighboring gene RIC3 acetylcholine receptor chaperone Neighboring gene NADH dehydrogenase (ubiquinone) B14.7 subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition. Zavortink M, et al. Elife, 2020 Jun 23. PMID 32573431, Free PMC Article
  2. dCas9-targeted locus-specific protein isolation method identifies histone gene regulators. Tsui C, et al. Proc Natl Acad Sci U S A, 2018 Mar 20. PMID 29507191, Free PMC Article
  3. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cao WX, et al. Cell Rep, 2020 Jun 23. PMID 32579915, Free PMC Article
  4. Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. Finan D, et al. Proc Natl Acad Sci U S A, 2011 Apr 5. PMID 21368190, Free PMC Article
  5. Characteristics and expression of lncRNA and transposable elements in Drosophila aneuploidy. Zhang S, et al. iScience, 2023 Dec 15. PMID 38125016, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
contributes_to ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of GID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of GID complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
souji
Names
CG3295-PA
Sou-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21015594..21017446 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137692.3 → NP_611536.1  souji [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611536.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2N5
    Related
    FBpp0071476
    Conserved Domains (5) summary
    smart00667
    Location:152 → 181
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:193 → 250
    CTLH; C-terminal to LisH motif
    smart00757
    Location:252 → 343
    CRA; CT11-RanBPM
    COG5109
    Location:88 → 432
    COG5109; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    pfam13445
    Location:377 → 416
    zf-RING_UBOX; RING-type zinc-finger
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W2N5 Q9W2N5

Gene LinkOut

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