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Gar1 Gar1 ribonucleoprotein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37397, updated on 4-Jan-2025

Summary

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Official Symbol
Gar1provided by FlyBase
Official Full Name
Gar1 ribonucleoproteinprovided by FlyBase
Primary source
FLYBASE:FBgn0011824
Locus tag
Dmel_CG4038
See related
AllianceGenome:FB:FBgn0011824
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-Pen101; CG4038; CG4038-PA; dGAR1; Dmel\CG4038; GAR1; GCR 101; GCR101; GCR101 SnRNP; Pen101
Summary
Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in snoRNA guided rRNA pseudouridine synthesis. Located in nucleolus and nucleoplasm. Is expressed in several structures, including adult brain cell body rind; adult fat body; adult heart; embryonic/larval midgut primordium; and larval muscle cell. Orthologous to human GAR1 (GAR1 ribonucleoprotein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Gar1 in Genome Data Viewer
Location:
57B20-57B20; 2-92 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21095958..21097305, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16983463..16984810, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44704 Neighboring gene uncharacterized protein Neighboring gene Trehalase Neighboring gene Rabaptin-5 Neighboring gene uncharacterized protein Neighboring gene king tubby Neighboring gene uncharacterized protein Neighboring gene Transmembrane O-mannosyltransferase targeting cadherins 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of a distinct genomic domain in Drosophila: comparative analysis of the dot chromosome in Drosophila melanogaster and Drosophila virilis. Leung W, et al. Genetics, 2010 Aug. PMID 20479145, Free PMC Article
  2. Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila. Pasquier C, et al. Life Sci Alliance, 2022 Feb. PMID 34844981, Free PMC Article
  3. Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster. Thomas C, et al. Dev Biol, 2014 Jan 1. PMID 24104056, Free PMC Article
  4. PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth. Ciurciu A, et al. PLoS Genet, 2013 Oct. PMID 24204300, Free PMC Article
  5. Native purification of protein and RNA-protein complexes using a novel affinity procedure. Kroiss M, et al. Fly (Austin), 2009 Jul-Sep. PMID 19690462

See all (54) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables box H/ACA snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in pseudouridine synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA pseudouridine synthesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in snoRNA guided rRNA pseudouridine synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of box H/ACA snoRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of box H/ACA snoRNP complex TAS
Traceable Author Statement
more info
 PubMed 
located_in nucleolus HDA PubMed 
located_in nucleoplasm HDA PubMed 
part_of sno(s)RNA-containing ribonucleoprotein complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Gar1 ribonucleoprotein
Names
CG4038-PA
Gar1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21095958..21097305 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057695.4 → NP_477043.1  Gar1 ribonucleoprotein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477043.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24345, Q7KVQ0, Q86R95, Q9W2L8
    UniProtKB/TrEMBL
    A8E6K0
    Related
    FBpp0071562
    Conserved Domains (1) summary
    pfam04410
    Location:61 → 162
    Gar1; Gar1/Naf1 RNA binding region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KVQ0.1 Q7KVQ0

Gene LinkOut

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