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UNG uracil DNA glycosylase [ Gallus gallus (chicken) ]

Gene ID: 374010, updated on 3-Dec-2024

Summary

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Symbol
UNGprovided by CGNC
Full Name
uracil DNA glycosylaseprovided by CGNC
Primary source
CGNC:49003
See related
Ensembl:ENSGALG00010021483
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See UNG in Genome Data Viewer
Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (6665723..6670040)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (6676305..6680623)

Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene SV2 related protein Neighboring gene ubiquitin specific peptidase 30 Neighboring gene alkB homolog 2, alpha-ketoglutarate dependent dioxygenase Neighboring gene microRNA 6648-1 Neighboring gene acetyl-CoA carboxylase beta Neighboring gene forkhead box N4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Di Noia J, et al. Nature, 2002 Sep 5. PMID 12214226
  2. Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus. Chowdhury S, et al. FEBS Lett, 2013 Sep 17. PMID 23954625
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus.
    Title: Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables uracil DNA N-glycosylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in base-excision repair, AP site formation via deaminated base removal IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
uracil-DNA glycosylase
NP_001385002.1
NP_989520.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398073.1 → NP_001385002.1  uracil-DNA glycosylase isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000260
    UniProtKB/TrEMBL
    Q8AYC6

  2. NM_204189.2 → NP_989520.2  uracil-DNA glycosylase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000260
    UniProtKB/TrEMBL
    F1NJG2, Q8AYC6
    Related
    ENSGALP00010031103.1, ENSGALT00010052091.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6665723..6670040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6676305..6680623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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