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CG10344 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37565, updated on 9-Dec-2024

Summary

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Official Symbol
CG10344provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034729
Locus tag
Dmel_CG10344
See related
AllianceGenome:FB:FBgn0034729
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10344
Summary
Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Located in endoplasmic reticulum. Is expressed in larval central nervous system and organism. Orthologous to human ZDHHC24 (zinc finger DHHC-type containing 24). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG10344 in Genome Data Viewer
Location:
58E1-58E1; 2-100 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22425733..22426977, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18313238..18314482, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene quaking related 58E-2 Neighboring gene mitochondrial ribosomal protein S29 Neighboring gene rad50 Neighboring gene uncharacterized protein Neighboring gene pickpocket 12 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense. Deng Z, et al. J Genet Genomics, 2023 Dec. PMID 37343788
  2. The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. Bannan BA, et al. Fly (Austin), 2008 Jul-Aug. PMID 18719403, Free PMC Article
  3. A deletion-generator compound element allows deletion saturation analysis for genomewide phenotypic annotation. Huet F, et al. Proc Natl Acad Sci U S A, 2002 Jul 23. PMID 12096187, Free PMC Article
  4. Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1. Zhang T, et al. J Cell Sci, 2015 Aug 1. PMID 26092939, Free PMC Article
  5. Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Zhou R, et al. Mol Cell, 2008 Nov 21. PMID 19026789, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables palmitoyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-cysteine S-palmitoyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-cysteine S-palmitoyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG10344-PA
CG10344-PB
NP_611671.1
NP_726201.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22425733..22426977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166534.3 → NP_726201.1  uncharacterized protein Dmel_CG10344, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726201.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3PFF3, Q8MKK7
    Related
    FBpp0071751
    Conserved Domains (1) summary
    cl19890
    Location:93 → 178
    zf-DHHC; DHHC palmitoyltransferase

  2. NM_137827.3 → NP_611671.1  uncharacterized protein Dmel_CG10344, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611671.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W251
    Related
    FBpp0071752
    Conserved Domains (1) summary
    pfam01529
    Location:93 → 220
    zf-DHHC; DHHC palmitoyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MKK7 Q8MKK7
Q9W251 Q9W251

Gene LinkOut

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