U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG4610 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37571, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
CG4610provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034735
Locus tag
Dmel_CG4610
See related
AllianceGenome:FB:FBgn0034735
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4610
Summary
Predicted to enable flavin adenine dinucleotide binding activity. Predicted to be involved in mitochondrial tRNA wobble uridine modification and tRNA methylation. Predicted to be active in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 10. Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG4610 in Genome Data Viewer
Location:
58E3-58E4; 2-100 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22492197..22494295)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18379702..18381800)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene plexus Neighboring gene gasoline Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Helena and BS: Two Travellers between the Genera Drosophila and Zaprionus. Simão MC, et al. Genome Biol Evol, 2018 Oct 1. PMID 30165545, Free PMC Article
  2. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Jin W, et al. Nat Genet, 2001 Dec. PMID 11726925
  3. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
  4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial tRNA wobble uridine modification IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA wobble uridine modification IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG4610-PA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22492197..22494295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137833.2 → NP_611677.1  uncharacterized protein Dmel_CG4610 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611677.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W245
    Related
    FBpp0071745
    Conserved Domains (3) summary
    PRK05192
    Location:28 → 661
    PRK05192; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated
    pfam13932
    Location:432 → 647
    GIDA_assoc; GidA associated domain
    cl21454
    Location:33 → 450
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W245 Q9W245

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools