CycB - Cyclin B

Enables cyclin-dependent protein serine/threonine kinase regulator activity. Involved in several processes, including G2/M transition of mitotic cell cycle; midbody abscission; and nuclear chromosome segregation. Located in nucleus and spindle midzone. Colocalizes with mitotic spindle. Is expressed in several structures, including antennal primordium; ganglia; germline cell; head epidermis primordium; and optic neuroblast. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to several human genes including CCNB1 (cyclin B1). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

How was this calculated?