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His2A:CG33859 histone H2A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772139, updated on 4-Jan-2025

Summary

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Official Symbol
His2A:CG33859provided by FlyBase
Official Full Name
histone H2Aprovided by FlyBase
Primary source
FLYBASE:FBgn0053859
Locus tag
Dmel_CG33859
See related
AllianceGenome:FB:FBgn0053859
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG33859; Dmel\CG33859
Summary
Predicted to enable DNA binding activity. Predicted to be involved in chromatin organization. Predicted to be part of nucleosome. Orthologous to several human genes including H2AC11 (H2A clustered histone 11); H2AC12 (H2A clustered histone 12); and H2AC13 (H2A clustered histone 13). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See His2A:CG33859 in Genome Data Viewer
Location:
39E1-39E1; 2-54 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21528341..21528833)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21528341..21528833)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene histone H1 Neighboring gene histone H2B Neighboring gene small non-coding RNA 430r Neighboring gene histone H4 Neighboring gene histone H3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article
  2. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867, Free PMC Article
  3. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856, Free PMC Article
  4. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336, Free PMC Article
  5. Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. Hoskins RA, et al. Genome Biol, 2002. PMID 12537574, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromatin organization ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  
part_of nucleosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
histone H2A
Names
CG33859-PA
His2A:CG33859-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    21528341..21528833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001032205.2 → NP_001027376.1  histone H2A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027376.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4AB57
    Conserved Domains (2) summary
    smart00414
    Location:16 → 121
    H2A; Histone 2A
    cd00074
    Location:16 → 119
    H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4AB57 Q4AB57

Gene LinkOut

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