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mi minus [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37723, updated on 9-Dec-2024

Summary

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Official Symbol
miprovided by FlyBase
Official Full Name
minusprovided by FlyBase
Primary source
FLYBASE:FBgn0261786
Locus tag
Dmel_CG5360
See related
AllianceGenome:FB:FBgn0261786
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5360; Dmel\CG5360; l(2)SH0818; l(2)SH2 0818
Summary
Enables SCF ubiquitin ligase complex binding activity and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; chaeta morphogenesis; and endomitotic cell cycle. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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Location:
59E2-59E2; 2-103 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23523856..23528260)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19411379..19415783)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RabX1 Neighboring gene brown Neighboring gene pickpocket 3 Neighboring gene Gustatory receptor 59e

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of chromatin structure of genes silenced by heterochromatin in trans. Nisha P, et al. Genetics, 2008 May. PMID 18493059, Free PMC Article
  2. Drosophila Minus is required for cell proliferation and influences Cyclin E turnover. Szuplewski S, et al. Genes Dev, 2009 Sep 1. PMID 19723762, Free PMC Article
  3. Mutants affecting position-effect heterochromatinization in Drosophila melanogaster. Reuter G, et al. Chromosoma, 1982. PMID 6813058
  4. Morphogenesis of denticles and hairs in Drosophila embryos: involvement of actin-associated proteins that also affect adult structures. Dickinson WJ, et al. Cell Motil Cytoskeleton, 1997. PMID 9295137
  5. A misexpression screen to identify regulators of Drosophila larval hemocyte development. Stofanko M, et al. Genetics, 2008 Sep. PMID 18757933, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables SCF ubiquitin ligase complex binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables ubiquitin-like ligase-substrate adaptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chaeta morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endomitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ovarian nurse cell to oocyte transport HMP PubMed 
involved_in positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
minus
Names
CG5360-PA
lethal (2) SH0818
mi-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23523856..23528260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137959.2 → NP_611803.1  minus [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611803.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W1N8
    Related
    FBpp0071967
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W1N8 Q9W1N8

Gene LinkOut

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