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His4:CG33879 histone H4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772319, updated on 9-Dec-2024

Summary

Official Symbol
His4:CG33879provided by FlyBase
Official Full Name
histone H4provided by FlyBase
Primary source
FLYBASE:FBgn0053879
Locus tag
Dmel_CG33879
See related
AllianceGenome:FB:FBgn0053879
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG33879; Dmel\CG33879
Summary
Enables DNA binding activity. Involved in nucleosome assembly. Located in nuclear chromosome. Part of RCAF complex and nucleosome. Orthologous to several human genes including H4C1 (H4 clustered histone 1); H4C11 (H4 clustered histone 11); and H4C12 (H4 clustered histone 12). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See His4:CG33879 in Genome Data Viewer
Location:
39D5-39D5; 2-54 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21509422..21509834, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21509422..21509834, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene histone H2B Neighboring gene histone H2A Neighboring gene small non-coding RNA 430n Neighboring gene histone H3 Neighboring gene histone H1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in nucleosome assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nucleosome assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of RCAF complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
part_of nucleosome IDA
Inferred from Direct Assay
more info
PubMed 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
part_of nucleosome ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
histone H4
Names
CG33879-PA
His4:CG33879-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    21509422..21509834 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001032186.2NP_001027357.1  histone H4 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027357.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P84040
    Conserved Domains (2) summary
    PLN00035
    Location:1103
    PLN00035; histone H4; Provisional
    cd00076
    Location:18101
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...