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His2A:CG33817 histone H2A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772351, updated on 9-Dec-2024

Summary

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Official Symbol
His2A:CG33817provided by FlyBase
Official Full Name
histone H2Aprovided by FlyBase
Primary source
FLYBASE:FBgn0053817
Locus tag
Dmel_CG33817
See related
AllianceGenome:FB:FBgn0053817
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG33817; Dmel\CG33817
Summary
Predicted to enable DNA binding activity. Involved in larval somatic muscle development. Located in nucleus and polytene chromosome band. Orthologous to several human genes including H2AC11 (H2A clustered histone 11); H2AC12 (H2A clustered histone 12); and H2AC13 (H2A clustered histone 13). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See His2A:CG33817 in Genome Data Viewer
Location:
39D4-39D4; 2-54 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21457995..21458487)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21457995..21458487)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene histone H1 Neighboring gene histone H2B Neighboring gene small non-coding RNA 430d Neighboring gene histone H4 Neighboring gene histone H3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. tRNA derived insertion element in histone gene repeating unit of Drosophila melanogaster. Matsuo Y, et al. Nucleic Acids Res, 1989 Jan 11. PMID 2536150, Free PMC Article
  2. Histone H2A.Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogaster. Leach TJ, et al. J Biol Chem, 2000 Jul 28. PMID 10801889
  3. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
  4. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article
  5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables DNA binding NAS
Non-traceable Author Statement
more info
 PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromatin organization ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in larval somatic muscle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleosome assembly NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  
part_of nucleosome ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of nucleosome NAS
Non-traceable Author Statement
more info
 PubMed 
part_of nucleosome TAS
Traceable Author Statement
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in polytene chromosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in polytene chromosome band IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
histone H2A
Names
CG33817-PA
His2A:CG33817-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    21457995..21458487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001032135.2 → NP_001027306.1  histone H2A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027306.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P84051, Q4ABC7
    Conserved Domains (1) summary
    PTZ00017
    Location:16 → 124
    PTZ00017; histone H2A; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P84051.2 P84051

Gene LinkOut

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