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SLIRP1 SRA stem-loop interacting RNA binding protein 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772560, updated on 9-Dec-2024

Summary

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Official Symbol
SLIRP1provided by FlyBase
Official Full Name
SRA stem-loop interacting RNA binding protein 1provided by FlyBase
Primary source
FLYBASE:FBgn0064117
Locus tag
Dmel_CG33714
See related
AllianceGenome:FB:FBgn0064117
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg1704; CG1704; CG33071; CG33071-ORFA; CG33071ORFA; CG33714; Dmel\CG33714; DmSLIRP1; Dromel_CG33713_FBtr0091704_uORF; RRM
Summary
Predicted to enable mRNA binding activity. Predicted to be active in nucleus. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; gut section; larval somatic muscle cell; and mesoderm. Orthologous to human SLIRP (SRA stem-loop interacting RNA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See SLIRP1 in Genome Data Viewer
Location:
19F4-19F4; 1-65 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21317936..21319296, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21188963..21190323, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 3 Neighboring gene transfer RNA:Tyrosine-GTA 2-1 Neighboring gene uncharacterized protein Neighboring gene Regulatory particle triple-A ATPase 6 Neighboring gene anorexia Neighboring gene Dullard Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A gene involved in the food preferences of larval Drosophila melanogaster. Ryuda M, et al. J Insect Physiol, 2008 Oct-Nov. PMID 18773904
  2. Identification of a novel gene, anorexia, regulating feeding activity via insulin signaling in Drosophila melanogaster. Ryuda M, et al. J Biol Chem, 2011 Nov 4. PMID 21917925, Free PMC Article
  3. Anti-ageing effects of red ginseng on female Drosophila melanogaster. Hou W, et al. J Cell Mol Med, 2020 Mar. PMID 32022406, Free PMC Article
  4. Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. Liu Z, et al. Dev Growth Differ, 2011 Aug. PMID 21790556
  5. Drosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation. Matsushima Y, et al. Sci Rep, 2017 Aug 16. PMID 28814717, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial matrix TAS
Traceable Author Statement
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SRA stem-loop interacting RNA binding protein 1
Names
CG33714-PA
CG33714-PB
CPuORF of FBgn0064116
SLIRP1-PA
SLIRP1-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    21317936..21319296 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001031912.2 → NP_001027083.1  SRA stem-loop interacting RNA binding protein 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027083.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHQ1
    Conserved Domains (1) summary
    cd12242
    Location:16 → 88
    RRM_SLIRP; RNA recognition motif (RRM) found in SRA stem-loop-interacting RNA-binding protein (SLIRP) and similar proteins

  2. NM_001031913.2 → NP_001027084.1  SRA stem-loop interacting RNA binding protein 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027084.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHQ1
    Conserved Domains (1) summary
    cd12242
    Location:16 → 88
    RRM_SLIRP; RNA recognition motif (RRM) found in SRA stem-loop-interacting RNA-binding protein (SLIRP) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0KHQ1 Q0KHQ1

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