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Eglp1 Entomoglyceroporin 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37736, updated on 4-Jan-2025

Summary

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Official Symbol
Eglp1provided by FlyBase
Official Full Name
Entomoglyceroporin 1provided by FlyBase
Primary source
FLYBASE:FBgn0034882
Locus tag
Dmel_CG5398
See related
AllianceGenome:FB:FBgn0034882
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.151; Aqp5398; CG5398; Dmel\CG5398; Eglp 1
Summary
Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. Orthologous to human AQP6 (aquaporin 6). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Eglp1 in Genome Data Viewer
Location:
59F4-59F4; 2-104 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23602585..23603641)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19490108..19491164)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Immune induced molecule 18 Neighboring gene uncharacterized protein Neighboring gene Entomoglyceroporin 2 Neighboring gene Entomoglyceroporin 3 Neighboring gene Entomoglyceroporin 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin. Kaufmann N, et al. Am J Physiol Cell Physiol, 2005 Aug. PMID 15800049
  2. Insect glycerol transporters evolved by functional co-option and gene replacement. Finn RN, et al. Nat Commun, 2015 Jul 17. PMID 26183829, Free PMC Article
  3. Genetic mapping with SNP markers in Drosophila. Berger J, et al. Nat Genet, 2001 Dec. PMID 11726933
  4. Computational identification of Ftz/Ftz-F1 downstream target genes. Bowler T, et al. Dev Biol, 2006 Nov 1. PMID 16996052
  5. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Jin W, et al. Nat Genet, 2001 Dec. PMID 11726925

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables channel activity IEA
Inferred from Electronic Annotation
more info
  
enables channel activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
entomoglyceroporin 1
Names
CG5398-PA
Eglp1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23602585..23603641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137966.2 → NP_611810.1  entomoglyceroporin 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611810.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W1M4
    Related
    FBpp0071980, FBtr0072071
    Conserved Domains (1) summary
    cl00200
    Location:13 → 223
    MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W1M4 Q9W1M4

Gene LinkOut

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